IL-1 -induced and p38-dependent activation of the mitogen-activated protein kinase-activated protein kinase 2 (MK2) in hepatocytes: Signal transduction with robust and concentration-independent signal amplification
نویسندگان
چکیده
Andreas Kulawik, Raphael Engesser, Christian Ehlting, Andreas Raue, Ute Albrecht, Bettina Hahn , Wolf-Dieter Lehmann , Matthias Gaestel**, Ursula Klingmüller, Dieter Häussinger, Jens Timmer, and Johannes G. Bode From the Department of Gastroenterology, Hepatology, and Infectious Disease, University Hospital, Heinrich Heine University, Moorenstraße 5, 40225 Düsseldorf, Germany, the Institute of Physics, University of Freiburg, Hermann-Herder-Straße 3, 79104 Freiburg, Germany, Molecular Structure Analysis and Division of Systems Biology of Signal Transduction, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany, the **Institute of Physiological Chemistry, Hannover Medical School, 30625 Hannover, Germany, and the BIOSS Centre for Biological Signaling Studies, University of Freiburg, Schänzlestraße 18, 79104 Freiburg, Germany
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